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Mutagenesis. 1992 Jan;7(1):83-5.

Chromosomal localization of human O6-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization.

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1
MGC Department of Radiation Genetics and Chemical Mutagenesis, State University of Leiden, The Netherlands.

Abstract

Recombinant lambda phage DNA containing segments of human O6-methylguanine-DNA transferase gene was employed to localize this gene among the human chromosomes using non-radioactive in situ hybridization technique. This gene was found to be present at the telomeric end, 26q, of the long arm of the chromosome 10.

PMID:
1635460
[Indexed for MEDLINE]
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