Format

Send to

Choose Destination
J Am Chem Soc. 2005 Dec 21;127(50):17604-5.

Bright fluorescent nanodiamonds: no photobleaching and low cytotoxicity.

Author information

1
Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan 106, ROC.

Abstract

Diamond nanocrystals emit bright fluorescence at 600-800 nm after irradiation by a 3 MeV proton beam (5 x 1015 ions/cm2) and annealing at 800 degrees C (2 h) in vacuum. The irradiation/annealing process yields high concentrations of nitrogen-vacancy defect centers ( approximately 107 centers/mum3), making possible visualization of the individual 100 nm diamond crystallites using a fluorescence microscope. The fluorescent nanodiamonds (FND) show no sign of photobleaching and can be taken up by mammalian cells with minimal cytotoxicity. The nanomaterial can have far-reaching biological applications.

PMID:
16351080
DOI:
10.1021/ja0567081
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Chemical Society
Loading ...
Support Center