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J Fluoresc. 2005 Sep;15(5):729-33.

The fluorescence bioassay platforms on quantum dots nanoparticles.

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  • 1College of Life Science & Technology, Huazhong University of Science and Technology, Wuhan, P. R. China, 430074.


In this paper, we present the optical properties and the platforms on fluorescent quantum dots for biological labeling, biomedical engineering and biosensor in molecular imaging. Quantum dots possess several properties that make them very attractive for fluorescent tagging: broad excitation spectrum, narrow emission spectrum, precise tunability of their emission peak, longer fluorescence lifetime than organic fluorophores and negligible photobleaching. We describe how to take such advantages of quantum dots to develop the technology and employ it to build assay platforms. Finally, ultrasensitivity, multicolor, and multiplexing of the technology of semiconductor quantum dots open up promising and interesting possibilities for bioassay platform.

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