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J Exp Med. 2005 Dec 5;202(11):1459-63.

Regulatory T cells and IL-10 in allergic inflammation.

Author information

1
Medical Research Council and Asthma UK Centre for Allergic Mechanisms in Asthma, King's College London, London SE1 9RT, UK. C.M.H.catherine.hawrylowicz@kcl.ac.uk

Abstract

Recent studies suggest that human regulatory T (T reg) cells protect against the development of allergic and asthmatic disease and that their function is impaired during active disease. Two new studies contribute to our understanding of the role that T reg cells play in the control of allergic airway disease in mice. However, these studies also highlight several outstanding questions in the field.

PMID:
16330811
PMCID:
PMC2213335
DOI:
10.1084/jem.20052211
[Indexed for MEDLINE]
Free PMC Article
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