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Am J Psychiatry. 2005 Dec;162(12):2389-91.

Research advance directives: protection or obstacle?

Author information

1
Department of Clinical Bioethics, NIH, Bldg. 10, Rm. 1C118, Bethesda, MD 20892, USA.

Abstract

OBJECTIVE:

This study assessed how many adults completed a research advance directive and the preferences indicated on the completed forms.

METHOD:

The authors analyzed all 2,371 adults admitted as inpatients to the NIH Clinical Center from March 14 to Sept. 13, 2000.

RESULTS:

Overall, 11% of adult inpatients completed a research advance directive. Of those who specified preferences, 13% were not willing to participate in future research should they become unable to consent, 76% were willing to participate in research that might help them, 49% were willing to participate in research that would not help them and posed minimal risk, and 9% were willing to participate in research that would not help them and posed greater than minimal risk.

CONCLUSIONS:

Proposals to allow cognitively impaired adults to participate in research only with a formal advance directive could block important research. More flexible approaches should be considered to protect these individuals.

PMID:
16330609
DOI:
10.1176/appi.ajp.162.12.2389
[Indexed for MEDLINE]
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