Comorbidity of obsessive-compulsive disorder and attention-deficit/hyperactivity disorder in referred children and adolescents

Compr Psychiatry. 2006 Jan-Feb;47(1):42-7. doi: 10.1016/j.comppsych.2005.04.008.

Abstract

Objective: The aim of this study was to explore whether comorbid attention-deficit/hyperactivity disorder (ADHD) affects the clinical expression and outcome of obsessive-compulsive disorder (OCD) in a clinical sample.

Method: A consecutive series of 94 children and adolescents (mean age, 13.6 +/- 2.8 years) with current diagnosis of OCD were included in the study. Twenty-four (25.5%) patients were diagnosed as having a comorbid ADHD. Subjects with OCD plus ADHD were compared with subjects with OCD but without ADHD.

Results: Comorbid ADHD with OCD was significantly associated with a higher rate of males, an earlier onset of OCD, a greater psychosocial impairment, and a heavier comorbidity, namely, with bipolar disorder, tic disorder, and oppositional defiant disorder/conduct disorder. Phenomenology of obsessions and compulsions and outcome were not affected by ADHD comorbidity.

Conclusions: A screening for ADHD should be performed in patients with OCD, as these patients and their parents are frequently not aware that the impairment may be partly due to a comorbid ADHD.

MeSH terms

  • Adolescent
  • Age of Onset
  • Analysis of Variance
  • Attention Deficit Disorder with Hyperactivity / epidemiology*
  • Child
  • Comorbidity
  • Female
  • Humans
  • Italy / epidemiology
  • Male
  • Mental Disorders / epidemiology
  • Obsessive-Compulsive Disorder / drug therapy*
  • Obsessive-Compulsive Disorder / epidemiology*
  • Obsessive-Compulsive Disorder / psychology
  • Selective Serotonin Reuptake Inhibitors / therapeutic use*
  • Sex Distribution
  • Statistics, Nonparametric
  • Treatment Outcome

Substances

  • Serotonin Uptake Inhibitors