Format

Send to

Choose Destination
See comment in PubMed Commons below
Ann Rheum Dis. 2006 Jul;65(7):936-41. Epub 2005 Dec 1.

EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides.

Author information

1
Department of Paediatrics, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey, and Paediatric Nephrology, Institute of Child Health and Great Ormond Street Hospital for Sick Children, London, UK. sezaozen@hacettepe.edu.tr

Abstract

BACKGROUND:

There has been a lack of appropriate classification criteria for vasculitis in children.

OBJECTIVE:

To develop a widely accepted general classification for the vasculitides observed in children and specific and realistic classification criteria for common childhood vasculitides (Henoch-Schönlein purpura (HSP), Kawasaki disease (KD), childhood polyarteritis nodosa (PAN), Wegener's granulomatosis (WG), and Takayasu arteritis (TA)).

METHODS:

The project was divided into two phases: (1) the Delphi technique was used to gather opinions from a wide spectrum of paediatric rheumatologists and nephrologists; (2) a consensus conference using nominal group technique was held. Ten international experts, all paediatricians, met for the consensus conference. Agreement of at least 80% of the participants was defined as consensus.

RESULTS:

Consensus was reached to base the general working classification for childhood vasculitides on vessel size. The small vessel disease was further subcategorised into "granulomatous" and "non-granulomatous." Final criteria were developed to classify a child as HSP, KD, childhood PAN, WG, or TA, with changes introduced based on paediatric experience. Mandatory criteria were suggested for all diseases except WG.

CONCLUSIONS:

It is hoped that the suggested criteria will be widely accepted around the world because of the reliable techniques used and the international and multispecialist composition of the expert group involved.

PMID:
16322081
PMCID:
PMC1798210
DOI:
10.1136/ard.2005.046300
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center