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Mol Cell. 2005 Nov 23;20(4):495-6.

SUMO changes Sox for developmental diversity.

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1
Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

Abstract

The finding that posttranslational modification of the SoxE transcription factors by SUMO regulates specific developmental programs (Taylor and LaBonne [2005], in the journal Developmental Cell) highlights the biological significance of SUMOylation in gene expression and underscores how much there is yet to learn about the function and regulation of this modification.

PMID:
16307912
DOI:
10.1016/j.molcel.2005.11.004
[Indexed for MEDLINE]
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