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J Gen Intern Med. 2005 Nov;20(11):1038-41.

Buprenorphine retention in primary care.

Author information

1
Division of General Internal Medicine, Rhode Island Hospital, Providence, RI 02903, USA. mstein@lifespan.org

Abstract

BACKGROUND:

This study assesses the rate and predictors of treatment retention for primary care patients with opioid dependence-prescribed buprenorphine, a long-acting partial opioid agonist.

METHODS:

Observational cohort study of patients prescribed buprenorphine/naloxone and followed for 6 months in the period after the adoption of buprenophine/naloxone by a primary care practice in Rhode Island. Practice policy precluded patient discharges due to continuing drug use.

RESULTS:

Patients (n=41) had a mean duration of opioid use of 15.7 years and most had a history of heroin use (63.4%). Thirty-nine percent of patients transferred from methadone maintenance. At 24 weeks, 59% remained in treatment. Nearly half of dropouts occurred in the first 30 days. Participants with opiate-positive toxicologies at week 1 were more likely to drop out of the program (P<.01) and had a significantly shorter retention time (P<.01) on average. Among other drug use and drug treatment variables, employment and addiction counseling during treatment were significantly associated with treatment retention (P=.03).

CONCLUSION:

Retention rates in a real world, primary care-based buprenorphine maintenance practice reflect those reported in clinical trials. Abstinence during the first week of treatment and receipt of counseling were critical to patient retention.

PMID:
16307630
PMCID:
PMC1490248
DOI:
10.1111/j.1525-1497.2005.0228.x
[Indexed for MEDLINE]
Free PMC Article

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