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Biosci Biotechnol Biochem. 2005 Nov;69(11):2219-23.

Effect of caffeine on the body fat and lipid metabolism of rats fed on a high-fat diet.

Author information

1
Department of Nutritional Sciences, Faculty of Applied Bio-Science, Tokyo University of Agriculture, Japan. k2kobaya@nodai.ac.jp

Abstract

The intake of caffeine (CF) at 0.025, 0.05 or 0.1% for 21 days progressively reduced the body fat mass and body fat percentage in Sprague-Dawley (SD) rats fed on a high-fat diet with increasing administration level. Moreover, CF increased the serum concentrations of catecholamines and free fatty acids in SD rats orally administered with CF (5 mg/kg). These results suggest that the intake of CF reduced body fat by lipolysis via catecholamines. CF has potential as a functional food ingredient with an anti-obesity action.

PMID:
16306706
DOI:
10.1271/bbb.69.2219
[Indexed for MEDLINE]
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