Description of a new HLA-DRB1*1104, DRB1*110403

Tissue Antigens. 2005 Dec;66(6):700-1. doi: 10.1111/j.1399-0039.2005.00484.x.

Abstract

We report here the exon 2 sequence of the novel HLA-DRB1*110403 which differs from DRB1*110401 by a single synonymous nucleotide substitution at codon 78, where TAC is substituted by TAT. The variant originally identified in a Caucasoid individual was confirmed by cloning and sequencing.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Base Sequence
  • Exons / genetics*
  • Genotype
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Haplotypes / genetics
  • Humans
  • Male
  • Molecular Sequence Data
  • Pedigree
  • Polymerase Chain Reaction
  • Polymorphism, Single-Stranded Conformational
  • Sequence Homology, Nucleic Acid
  • White People

Substances

  • HLA-DR Antigens
  • HLA-DRB1 Chains