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Acta Paediatr. 2005 Nov;94(11):1680-1.

Doxapram and developmental delay at 12 months in children born extremely preterm.

Author information

1
Department of Neonatology, The Juliane Marie Centre, Copenhagen University Hospital, Copenhagen, Denmark. alando@dadlnet.dk

Abstract

AIM:

To examine the relation of doxapram to a developmental score achieved by a structured telephone interview in a group of extremely-preterm-born children.

METHODS:

Parents of 88 children born extremely preterm were contacted by telephone and interviewed by a structured questionnaire (R-PDQ) when the corrected age of their child was 9-15 mo.

RESULTS:

We found that doxapram treatment was associated with a deficit in age-adjusted R-PDQ score.

CONCLUSION:

Doxapram may have a negative effect on neurodevelopmental outcome.

PMID:
16303710
DOI:
10.1080/08035250500254449
[Indexed for MEDLINE]

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