Autoimmune pancreatitis: unveiling a hidden entity

Arch Surg. 2005 Nov;140(11):1104-7. doi: 10.1001/archsurg.140.11.1104.

Abstract

Hypothesis: After alcohol-induced and hereditary disease, idiopathic chronic pancreatitis is the most common cause of calcifying pancreatitis. This designation is used when no associated cause of chronic pancreatitis is found. We present 6 cases of idiopathic pancreatitis in which the postoperative pathological examination results demonstrated lymphoplasmacytic sclerosing pancreatitis or autoimmune pancreatitis.

Design: Retrospective case series. The medical records of 6 patients referred and treated for autoimmune pancreatitis were reviewed. The duration of follow-up varies, the longest being 5 years. The disease and a literature review are reported.

Setting: A 200-bed community hospital located in a large city. The patients were referred after being treated elsewhere for recurrent pancreatitis.

Patients and methods: Six patients with chronic recurrent pancreatitis were evaluated. They were selected because pathological review indicated that they all had autoimmune pancreatitis.

Results: Six cases of lymphoplasmacytic sclerosing pancreatitis are presented and suggest that lymphoplasmacytic sclerosing pancreatitis should be thought of more often in chronic autoimmune pancreatitis.

Conclusion: Lymphoplasmacytic sclerosing pancreatitis is an increasingly recognized cause of chronic pancreatitis and should be considered in the evaluation of patients with chronic pancreatitis and no discernible cause.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Autoimmune Diseases / pathology*
  • Autoimmune Diseases / surgery*
  • Chronic Disease
  • Female
  • Humans
  • Pancreatitis / pathology*
  • Pancreatitis / surgery*
  • Recurrence