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Neuron. 2005 Nov 23;48(4):531-4.

Come together, right...now: synchronization of rhythms in a mammalian circadian clock.

Author information

1
Department of Biology, Washington University, St. Louis, Missouri 63130, USA.

Abstract

In mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus act as a dominant circadian pacemaker, coordinating rhythms throughout the body and regulating daily and seasonal changes in physiology and behavior. This review focuses on the mechanisms that mediate synchronization of circadian rhythms between SCN neurons. Understanding how these neurons communicate as a network of circadian oscillators has begun to shed light on the adaptability and dysfunction of the brain's master clock.

PMID:
16301169
PMCID:
PMC1780025
DOI:
10.1016/j.neuron.2005.11.001
[Indexed for MEDLINE]
Free PMC Article

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