Format

Send to

Choose Destination
J Med Virol. 2006 Jan;78(1):1-8.

Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals.

Author information

1
The Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York 10016, USA. lzhang@adarc.org

Abstract

Most of the SARS-CoV-infected patients spontaneously recovered without clinical intervention while a small percentage succumbed to the disease. Here, we characterized temporal changes in N protein-specific and S glycoprotein-specific neutralizing antibody (Nab) responses in infected patients who have either recovered from or succumbed to SARS-CoV infection. Recovered patients were found to have higher and sustainable levels of both N protein-specific and S glycoprotein-specific Nab responses, suggesting that antibody responses likely play an important role in determining the ultimate disease outcome of SARS-CoV-infected patients.

PMID:
16299724
DOI:
10.1002/jmv.20499
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center