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Breast J. 2005 Nov-Dec;11(6):457-61.

The distinctive role of positron emission tomography/computed tomography in breast carcinoma with brown adipose tissue 2-fluoro-2-deoxy-d-glucose uptake.

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Nuclear Medicine, Surgical Oncology and Medical Oncology Services, Saint Vincent's Comprehensive Cancer Center, Saint Vincent's Catholic Medical Center, and New York Medical College, New York, New York 10011, USA.


The diagnostic power of an integrated positron emission tomography/computed tomography (PET/CT) system for whole-body 2-fluoro-2-deoxy-d-glucose (FDG) imaging is clearly demonstrated in this case report. The precise anatomic localization of FDG uptake with CT in a PET/CT scan of a patient with known breast carcinoma helped identify a contralateral breast tumor with axillary lymph node metastasis despite the presence of extensive physiologic brown fat FDG uptake. Accordingly, the patient received appropriate surgical management and pathologic confirmation of the disease.

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