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Expert Opin Drug Deliv. 2005 May;2(3):563-77.

Nicotine delivery systems.

Author information

1
University of Pittsburgh Smoking Research Group, Department of Psychology, Pittsburgh, PA, USA. shiffman@pinneyassociates.com

Abstract

Over the past 20 years, medicinal nicotine has been used to aid smoking cessation, and has led to a significant increase in the number of smokers who successfully quit. This review describes currently available medicinal nicotine products, which include nicotine patch, gum, lozenge, nasal spray, inhaler and sublingual tablet, including their pharmacokinetics and recommended dosing. New developments in nicotine delivery that could further increase cessation rates include high-dose patches, rapid release gum, combined patch and acute forms, and several novel channels for nicotine delivery, such as nicotine drink, straw, lollipop and a pulmonary inhaler. New applications of existing and novel medicinal nicotine products may include relapse prevention, nicotine maintenance, temporary withdrawal management, reduced smoking and gradual quitting.

PMID:
16296775
DOI:
10.1517/17425247.2.3.563
[Indexed for MEDLINE]

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