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J Am Acad Audiol. 2005 Sep;16(8):564-73.

P1 latency as a biomarker for central auditory development in children with hearing impairment.

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Behavioral and Brian Sciences, Callier Advanced Hearing Research Center, University of Texas at Dallas 75235, USA.


We used the latency of the P1 cortical auditory-evoked potential (CAEP) as a biomarker for the development of central auditory pathways in three children who received intervention through hearing aids and/or cochlear implants. Our goal was to examine the clinical feasibility of using the latency of the P1 CAEP as an objective tool to evaluate whether acoustic amplification for hearing-impaired children has provided sufficient stimulation for normal development of central auditory pathways. If clinicians have such a marker, then they can more confidently make a decision about whether to provide a child with a cochlear implant following an appropriate hearing-aid trial. Using the same marker, clinicians will also be able to monitor the maturation of central auditory pathways once electrical stimulation is initiated.

[Indexed for MEDLINE]

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