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Respiration. 2008;75(2):211-4. Epub 2005 Nov 15.

Successful treatment of sarcoidosis-associated pulmonary hypertension with bosentan.

Author information

1
Division of Pulmonary/Critical Care Medicine, University of Connecticut School of Medicine, Farmington, Conn., USA. rfoley@uchc.edu

Abstract

Sarcoidosis is a systemic granulomatous disease of unknown etiology, in which the lungs and intrathoracic lymph nodes are predominant sites of involvement. Pulmonary hypertension is a known complication of sarcoidosis. Treatment of sarcoidosis-associated pulmonary hypertension has traditionally focused on the initiation of systemic corticosteroids, but has had inconsistent results. We present a patient with sarcoidosis-associated pulmonary hypertension who achieved substantial clinical improvement with the dual endothelin receptor antagonist bosentan.

PMID:
16293957
DOI:
10.1159/000089815
[Indexed for MEDLINE]

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