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Science. 2005 Nov 18;310(5751):1135-8.

Exploring and engineering the cell surface interface.

Author information

  • 1Department of Materials and Institute for Biomedical Engineering, Imperial College of Science, Technology, and Medicine, Prince Consort Road, London SW7 2BP, UK. m.stevens@imperial.ac.uk

Abstract

Cells are inherently sensitive to local mesoscale, microscale, and nanoscale patterns of chemistry and topography. We review current approaches to control cell behavior through the nanoscale engineering of materials surfaces. Far-reaching implications are emerging for applications including medical implants, cell supports, and materials that can be used as instructive three-dimensional environments for tissue regeneration.

PMID:
16293749
DOI:
10.1126/science.1106587
[PubMed - indexed for MEDLINE]
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