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Expert Rev Med Devices. 2005 Nov;2(6):667-71.

Degradable, drug-eluting stents: a new frontier for the treatment of coronary artery disease.

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1
New Jersey Center for Biomaterials, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA. Joachim@rutchem.Rutgers.edu

Abstract

This article reviews the clinical use of stents in the treatment of coronary artery disease and the rationale for the use of degradable, drug-eluting polymer stents. The authors note the challenges of using off-the-shelf polymers for the development of degradable stents, as well as the interplay between polymer properties and a functional stent design. Drug-eluting metal stents are the most significant advancement in the treatment of coronary artery disease, and have significantly reduced the occurrence of in-stent restenosis after placement. Some regard drug-eluting metal stents as the final technologic advancement in the treatment of coronary artery disease, others consider the future development of degradable, drug-eluting stents as the next logical step.

PMID:
16293093
DOI:
10.1586/17434440.2.6.667
[Indexed for MEDLINE]
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