Format

Send to

Choose Destination
See comment in PubMed Commons below
J Bacteriol. 2005 Dec;187(23):8205-10.

Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae.

Author information

1
Departments of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. wolfgang_haas@urmc.rochester.edu

Abstract

The vancomycin stress response was studied in Streptococcus pneumoniae strains T4 (TIGR4) and Tupelo. Vancomycin affected the expression of 175 genes, including genes encoding transport functions and enzymes involved in aminosugar metabolism. The two-component systems TCS03, TCS11, and CiaRH also responded to antibiotic treatment. We hypothesize that the three regulons are an important part of the bacterium's response to vancomycin stress.

PMID:
16291696
PMCID:
PMC1291284
DOI:
10.1128/JB.187.23.8205-8210.2005
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center