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Adv Drug Deliv Rev. 2005 Dec 14;57(15):2130-46. Epub 2005 Nov 11.

Characterization of dendrimers.

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  • 1Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, 31077 Toulouse Cedex 4, France.


Dendrimers pertain both to the molecular chemistry world for their step by step controlled syntheses, and to the polymer world because of their repetitive structure made of monomers; thus they benefit from analytical techniques from both worlds. This review is a survey of the main analytical techniques used for the characterization of the chemical composition, the morphology, the shape, and the homogeneity of dendrimers. It includes NMR, IR, Raman, UV-Visible, fluorescence, circular dichroism, X-ray diffraction, mass spectrometry, SAXS, SANS, Laser Light Scattering, microscopy, SEC, EPR, electrochemistry, electrophoresis, intrinsic viscosity, DSC, and dielectric spectroscopy.

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