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Toxicology. 2006 Jan 16;217(2-3):81-90. Epub 2005 Nov 9.

Biodegradation or metabolism of bisphenol A: from microorganisms to mammals.

Author information

1
Department of Applied Chemistry, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-Ku, Fukuoka 819-0395, Japan. jrjhkangtcm@mbox.nc.kyushu-u.ac.jp

Abstract

Bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane; CAS Registry No. 80-05-7) is one of endocrine disruptors and is made by combining acetone and phenol. BPA can be metabolized by extensive organisms. In this review these BPA biodegradations or metabolisms by many organisms from microorganisms to mammals were referred. Though the metabolites of BPA can enhance estrogenicity or toxicity, generally, BPA metabolism by organisms leads to detoxication of BPA.

PMID:
16288945
DOI:
10.1016/j.tox.2005.10.001
[Indexed for MEDLINE]

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