Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Lab. 2005;51(9-10):531-8.

Circulating endothelial cells: markers of vascular dysfunction.

Author information

1
Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK.

Abstract

Circulating endothelial cells (CEC) have evolved as a novel method of assessing endothelial function. Rarely found in the peripheral blood of healthy individuals, CECs increase in a wide variety of conditions such as cardiovascular disease, cancer, infection and inflammatory states. Unlike immature endothelial progenitor cells (EPC), which are bone marrow derived, CECs are felt to represent the detachment of mature endothelial cells from the endothelial monolayer, as a result of endothelial insult. In this article we present an overview of CECs and their association with a broad spectrum of disease processes.

PMID:
16285476
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center