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J Neurooncol. 2005 Nov;75(2):229-32.

Paraneoplastic limbic encephalitis presenting as acute viral encephalitis.

Abstract

OBJECTIVE:

To describe a case of limbic encephalitis which initially presented as viral limbic encephalitis and during the clinical evaluation a renal carcinoma was diagnosed.

CASE REPORT:

Patient with history of peripheral paresis of right facial nerve, 1 month after symptoms appearance and treatment, developed fever, vomiting, grand mal seizure, decreased level of consciousness, confusion, hallucinations and agitation. The patient initially presented a clinical picture of viral LE. which confirmed by CSF. MRI brain showed areas with pathological intensity signal in the region of limbic system unilateral. During the clinical evaluation a renal carcinoma was discovered and a nephrectomy has been performed.

CONCLUSIONS:

Although PLE typically presents as a chronic or subacute disease, it may be fulminant and clinically indistinguishable from an acute HSVE. This association pose the problem of a possible relation between this two syndromes and the correct diagnosis is very important, because there are effective treatments.

PMID:
16283448
DOI:
10.1007/s11060-005-3671-9
[Indexed for MEDLINE]

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