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Acta Neurol Scand. 2005 Dec;112(6):417-9.

Frequent association of multiple sclerosis with varicella and zoster.

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1
Neuroimmunology Unit, National Institute of Neurology and Neurosurgery of Mexico, Mexico City, Mexico.

Abstract

BACKGROUND:

A possible association of multiple sclerosis (MS) with viral diseases has been postulated; in previous studies we have found that in Mexican mestizos the antecedent of varicella during childhood represents a risk factor for the development of MS during adulthood.

AIM:

We conducted a retrospective search for varicella and zoster infections associated with the development of MS.

METHODS AND RESULTS:

In a cohort of 82 consecutive patients with MS we found six cases, four of varicella and two of zoster, that were concurrent with the development or the progress of MS.

CONCLUSIONS:

The association of these pathologies is higher than expected and suggests a possible etiological relationship of the varicella zoster virus with MS.

[Indexed for MEDLINE]

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