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Fertil Steril. 2005 Nov;84(5):1526-8.

Effect of cetrorelix acetate on apoptosis and apoptosis regulatory factors in cultured uterine leiomyoma cells.

Author information

1
Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea. jaykwon@yumc.yonsei.ac.kr

Abstract

This report suggests the possibility that a gonadotropin-releasing hormone (GnRH) antagonist initiates apoptosis not only by causing a sex hormone deficit by inhibiting GnRH secretion in the pituitary gland, but also by acting directly on leiomyoma cells promoting apoptosis.

[Indexed for MEDLINE]

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