Format

Send to

Choose Destination
See comment in PubMed Commons below
Crit Rev Biochem Mol Biol. 2005 Sep-Oct;40(5):243-67.

Ribosomal proteins in the spotlight.

Author information

1
Max-Planck-Institut für Molekulare Genetik, Berlin, Germany.

Abstract

The assignment of specific ribosomal functions to individual ribosomal proteins is difficult due to the enormous cooperativity of the ribosome; however, important roles for distinct ribosomal proteins are becoming evident. Although rRNA has a major role in certain aspects of ribosomal function, such as decoding and peptidyl-transferase activity, ribosomal proteins are nevertheless essential for the assembly and optimal functioning of the ribosome. This is particularly true in the context of interactions at the entrance pore for mRNA, for the translation-factor binding site and at the tunnel exit, where both chaperones and complexes associated with protein transport through membranes bind.

PMID:
16257826
DOI:
10.1080/10409230500256523
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center