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Curr Opin Microbiol. 2005 Dec;8(6):656-61. Epub 2005 Oct 26.

Archaeal chromatin proteins: different structures but common function?

Author information

1
Department of Microbiology, Ohio State University, 484W. 12th Avenue, Columbus, OH 43210, USA. sandman.1@osu.edu

Abstract

Chromatin proteins promote chromosome flexibility in vivo, maintaining a compact yet decondensed template that permits polymerase accessibility. All Archaea have at least two types of chromatin proteins, and diversity in the chromatin protein population appears to prevent polymerization of a single type of protein. Of the numerous chromatin proteins that have been described in Archaea, only two--histones and Alba homologs--are present in all archaeal phyla. Although their structures and complexes with DNA have no similarities, their functions probably overlap as mutants that lack single chromatin proteins are viable.

PMID:
16256418
DOI:
10.1016/j.mib.2005.10.007
[Indexed for MEDLINE]

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