Send to

Choose Destination
Curr Opin Microbiol. 2005 Dec;8(6):656-61. Epub 2005 Oct 26.

Archaeal chromatin proteins: different structures but common function?

Author information

Department of Microbiology, Ohio State University, 484W. 12th Avenue, Columbus, OH 43210, USA.


Chromatin proteins promote chromosome flexibility in vivo, maintaining a compact yet decondensed template that permits polymerase accessibility. All Archaea have at least two types of chromatin proteins, and diversity in the chromatin protein population appears to prevent polymerization of a single type of protein. Of the numerous chromatin proteins that have been described in Archaea, only two--histones and Alba homologs--are present in all archaeal phyla. Although their structures and complexes with DNA have no similarities, their functions probably overlap as mutants that lack single chromatin proteins are viable.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center