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Magn Reson Med. 1992 Jul;26(1):40-5.

Effects of the interaction between ferric iron and L-dopa melanin on T1 and T2 relaxation times determined by magnetic resonance imaging.

Author information

1
Psychiatry Service, Jerry L. Pettis Veterans' Affairs Medical Center, Loma Linda, California 92357.

Abstract

T1 and T2 relaxation times of agar phantoms containing L-dopa melanin and Fe3+ were measured under MRI conditions. Fe3+ shortened T1 and T2 relaxation times. Melanin influenced relaxation times only in the presence of Fe3+; thus, contrast in MR images of the basal ganglia may depend upon levels of both paramagnetic iron and neuromelanin.

PMID:
1625565
DOI:
10.1002/mrm.1910260105
[Indexed for MEDLINE]

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