Format

Send to

Choose Destination
See comment in PubMed Commons below
Eur J Clin Nutr. 2005 Nov;59 Suppl 2:S8-12.

Screening and recruitment procedure of late-middle aged and older subjects: the ZENITH study.

Author information

  • 1National Institute for Food and Nutrition Research, Human Nutrition Unit, Rome, Italy. polito@inran.it

Abstract

OBJECTIVE:

To report the rational, design, recruitment, baseline characteristics and preliminary overview of volunteers in the ZENITH study.

DESIGN:

A multicentre prospective intervention study employing a randomised double-blind design.

SETTING:

Clermont-Ferrand, Theix (France), Coleraine (Northern Ireland), Grenoble (France), Rome (Italy).

PARTICIPANTS:

Healthy men and women middle-aged (55-70 y) and older volunteers (70-87 y).

INTERVENTIONS:

At baseline (prior to zinc (Zn) supplementation), all volunteers underwent a full clinical examination, anthropometric measurements, health and lifestyle questionnaire, Mini Mental State Examination, Geriatric Depression Scale, and biochemistry profile.

RESULTS:

In total, 842 volunteers (378 men and 464 women) were invited to take part in the study. A total of 49% of these volunteers were excluded on the basis of inclusion/exclusion criteria. In total, 433 participants were admitted to the Zn supplementation for 6 months. During this period, about 10% of volunteers dropped out from the study.

CONCLUSIONS:

A total of 387 subjects (197 male and 190 female subjects) successfully completed the supplementation phase of the ZENITH study.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk