Format

Send to

Choose Destination
Biochem Soc Trans. 2006 Feb;34(Pt 1):30-4.

Control of mRNA stability in eukaryotes.

Author information

1
Institute of Cell and Molecular Biosciences, The Medical School, University of Newcastle, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK. s.f.newbury@ncl.ac.uk

Abstract

mRNA turnover plays a key role in the control of gene expression. Recent work has shown that proteins involved in mRNA turnover are located in multicomponent complexes which are tightly regulated. The control of mRNA stability is also intimately linked with translational processes. This article reviews the pathways and enzymes that control mRNA turnover in eukaryotic cells and discusses their mechanisms of control.

PMID:
16246172
DOI:
10.1042/BST20060030
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center