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Am J Respir Crit Care Med. 2006 Feb 1;173(3):256-63. Epub 2005 Oct 20.

The last 100 years of sepsis.

Author information

1
Department of Intensive Care, Erasme University Hospital, Brussels, Belgium 1070. jlvincen@ulb.ac.be

Abstract

Over the last 100 years, huge advances have been made in the field of sepsis in terms of pathophysiology, epidemiology, diagnosis, monitoring, and therapeutics. Here, we offer our perspective of the key changes and current situation in each of these areas. Despite these changes, mortality rates remain unacceptably high and continued progress, particularly in early diagnosis and therapy, is urgently needed.

PMID:
16239619
DOI:
10.1164/rccm.200510-1604OE
[Indexed for MEDLINE]

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