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J Sex Marital Ther. 2006 Jan-Feb;32(1):1-3.

Tadalafil reversal of sexual dysfunction caused by serotonin enhancing medications in women.

Author information

1
Buffalo Medical Group, Williamsville, New York 14221-5795, USA. aashton@buffalomedicalgroup.com

Abstract

Sexual dysfunction is a common side effect of many antidepressants, especially those that increase serotonin. Many strategies have been reported to assist patients in minimizing impairment, with variable degrees of success. One of the newer approaches is to augment with phosphodiesterase type-5 inhibitors. Our report using the most recently released agent in this class, tadalafil is the first demonstrating potential benefit in women. We report here of three women who derived benefit from using 20 mg of tadalafil before anticipated sexual activity to reverse medication-induced sexual dysfunction. Tadalafil utility was maintained over time and was well tolerated.

PMID:
16234221
DOI:
10.1080/00926230500229079
[Indexed for MEDLINE]

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