Format

Send to

Choose Destination
See comment in PubMed Commons below
J Biosci Bioeng. 2003;96(5):481-6.

An optimal model for representing the kinetics of growth and product formation by Lactobacillus rhamnosus on multiple substrates.

Author information

1
Department of Chemical Engineering, Indian Institute of Technology, Bombay, Powai, Mumbai-400076, India.

Abstract

A comprehensive model was developed to simulate Lactobacillus rhamnosus growth on a medium containing multiple limiting carbon sources. The strategy of optimizing specific growth rate to predict growth on multiple substrates was demonstrated. The model predictions were based on parameters obtained from L. rhamnosus growth on individual substrates. The model was able to simulate the growth, substrate consumption, product formation and specific growth rate profiles of L. rhamnosus accurately. The model prediction that co-metabolism of glucose and pyruvate enhances growth rate of and flavor production by the bacterium was experimentally verified.

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center