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Genes Dev. 2005 Oct 15;19(20):2407-11.

Surfing with the tunicates into the post-genome era.

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1
Department of Zoology, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

Abstract

This year is the centenary of Edward G. Conklin's signal findings in embryology: the elucidation of complete cell lineages and the discovery of localized maternal determinants. Conklin used ascidian embryos to elucidate universal principles in embryology. A century later, ascidians, or sea squirts, have not only entered the post-genome era, but in many ways are leading the way to the promise of a "systems-level" understanding of complex processes such as notochord formation, neurogenesis, and even behavior.

PMID:
16230530
PMCID:
PMC1257394
DOI:
10.1101/gad.1365805
[Indexed for MEDLINE]
Free PMC Article
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