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Vertex. 2005 Sep-Oct;16(63):332-41.

[Functional status and quality of life in Latin American outpatients with schizophrenia treated with atypical or typical antipsychotics: outcomes of the 12 months schizophrenia outpatient health outcomes (IC-SOHO) Study].

[Article in Spanish]

Author information

1
jrovner@lilly.com

Abstract

OBJECTIVE:

Functional status and quality of life outcomes in Latin American outpatients with schizophrenia were compared after 12 months of monotherapy treatment with olanzapine, risperidone or typical antipsychotics.

METHOD:

Both outcomes were assessed as part of a prospective, large (N= 7658), international (27 countries), observational study.

RESULTS:

from the Latin American subpopulation (N= 2671; 11 countries) are presented. Compared to typical antipsychotics, olanzapine and risperidone were associated with significantly (p < 0.05) greater odds of employment and social activity, and significantly greater improvements in quality of life. Olanzapine was also associated with significantly greater odds of living independently, compared to typical antipsychotics.

CONCLUSION:

This study indicates that functional status and quality of life outcomes are likely to be more favorable when Latin American outpatients with schizophrenia are treated with olanzapine or risperidone monotherapy, rather than typical antipsychotics.

PMID:
16220148
[Indexed for MEDLINE]

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