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Mol Gen Genet. 1992 Jun;233(3):483-6.

Riboflavin operon of Bacillus subtilis: unusual symmetric arrangement of the regulatory region.

Author information

1
Department of Molecular and Radiation Biophysics, Leningrad Nuclear Physics Institute of the Academy of Sciences of the USSR, Gatchina.

Abstract

Seventeen cis-dominant mutations leading to riboflavin overproduction in Bacillus subtilis were localized to the region between nucleotides +37 and +159 relative to the transcription initiation site of the riboflavin operon. This region displays an unusual structure for regulatory sequences. The main part of it represents clusters of A/T and G/C-rich sequences that symmetrically blank a short inverted repeat.

PMID:
1620102
DOI:
10.1007/bf00265448
[Indexed for MEDLINE]

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