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Obstet Gynecol. 2005 Oct;106(4):893-4.

ACOG committee opinion. Number 318, October 2005. Screening for Tay-Sachs disease.

Abstract

Tay-Sachs disease (TSD) is a severe progressive neurologic disease that causes death in early childhood. Carrier screening, should be offered before pregnancy to individuals and couples at high-risk, including those of Ashkenazi Jewish, French-Canadian, or Cajun descent and those with a family history consistent with TSD. If both partners are determined to be carriers of TSD, genetic counseling and prenatal diagnosis should be offered.

PMID:
16199656
[Indexed for MEDLINE]
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