Format

Send to

Choose Destination
J Bacteriol. 2005 Oct;187(20):7155-60.

YrxA is the transcriptional regulator that represses de novo NAD biosynthesis in Bacillus subtilis.

Author information

1
Dipartimento di Genetica e Microbiologia, Università degli Studi di Pavia, 1, Via Ferrata, 27100 Pavia, Italy.

Abstract

The first genetic, in vivo, and in vitro evidences that YrxA is the regulator of NAD de novo biosynthesis in Bacillus subtilis are hereby reported. The protein is essential to the transcription repression of the divergent operons nadBCA and nifS-yrxA in the presence of nicotinic acid and binds to their shared operator-promoter region.

PMID:
16199587
PMCID:
PMC1251630
DOI:
10.1128/JB.187.20.7155-7160.2005
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center