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Clin Exp Dermatol. 2005 Nov;30(6):646-8.

Myelofibrosis in a patient with pachydermoperiostosis.

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Service de Médecine Interne, Hôpital Tenon, Paris, France.


Pachydermoperiostosis (idiopathic or primary hypertrophic osteoarthropathy) is a rare condition of unknown origin involving the skin and the skeleton, with an autosomal dominant transmission. We report a case of anaemia in a patient with pachydermoperiostosis indicating myelofibrosis, and review the literature and the pathogenetic mechanisms.

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