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Behav Neurosci. 2005 Aug;119(4):1004-10.

Behavioral changes induced in rats by exposure to trimethylthiazoline, a component of fox odor.

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Tierphysiologie, Zoologisches Institut, Universität Tübingen, Tübingen, Germany.


Trimethylthiazoline (TMT), a component of fox feces, has been used in various studies as a natural predator stimulus to induce autonomic and behavioral signs of fear (e.g., higher levels of stress hormones, freezing, and risk assessment). The present study investigated whether 2 further behavioral signs of fear are induced in rats by TMT exposure: potentiation of the acoustic startle response and inhibition of appetitive behavior. In addition, the authors tested the rats for dose dependency of TMT-induced freezing behavior. The study confirmed that behavioral changes observed during TMT exposure are caused by TMT-induced fear and are dose dependent.

[Indexed for MEDLINE]

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