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Indian J Exp Biol. 2005 Sep;43(9):773-81.

Effect of spirulina and Liv-52 on cadmium induced toxicity in albino rats.

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Department of Biochemistry, Dr NGPArts & Science College, Kovai Medical Center Research & Educational Trust, Coimbatore 641 014, India.


Oral administration of cadmium (6mg/kg body weight/day) as cadmium chloride (CdCl2) for 30 days resulted in a significant increase in thiobarbituric acid reactive substances (TBARS) level and a decrease in the levels of copper, zinc, iron, selenium, glutathione, superoxide dismutase, catalase, glutathione peroxidase when compared to normal control. Administration of either Liv-52 alone or in combination with spirulina produced a well pronounced protective effect in respect to these parameters in cadmium intoxicated rats. The protective effect of spirulina and Liv-52 in respect to biochemical changes were also confirmed by histopathological study in the liver and kidney sections.

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