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Org Biomol Chem. 2005 Aug 21;3(16):2946-52. Epub 2005 Jul 19.

Synthesis and stability of exocyclic triazine nucleosides.

Author information

1
Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093-0358, USA.

Abstract

Synthesis and stability studies of exocyclic amino triazine nucleosides were performed. Stability of the nucleosides was found to be dependent on triazine ring electron density, solvent, and pH. The nucleosides were found to be more stable when the triazine ring was electron deficient, in high pH aqueous solutions and in aprotic solvents.

PMID:
16186926
DOI:
10.1039/b503757c
[Indexed for MEDLINE]

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