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Brain Res Dev Brain Res. 2005 Nov 7;160(1):106-11. Epub 2005 Sep 26.

Switching of alpha-catenin from alphaE-catenin in the cortical ventricular zone to alphaN-catenin II in the intermediate zone.

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Department of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.


Although cadherins and catenins are known to play important roles during neural development, the types of alpha-catenin present in the developing telencephalon are still unknown. Here, we show that the ventricular zones (VZ) of the cortex and the ganglionic eminences express alphaE-catenin and alphaN-catenin, respectively, in a complementary manner. In the cortex, alpha-catenin is switched from alphaE-catenin in the VZ to alphaN-catenin II in the intermediate zone (IMZ).

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