Glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome

Am J Kidney Dis. 2005 Oct;46(4):e55-8. doi: 10.1053/j.ajkd.2005.05.034.

Abstract

Glomerular tip lesion and its relation to different glomerular diseases is a subject of controversy. The therapeutic and prognostic clinical implications of glomerular tip lesions are ambiguous. We present a case of glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome that further complicates this issue. To our knowledge, this is the first case report of glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome.

Publication types

  • Case Reports

MeSH terms

  • Accidents, Traffic
  • Acetaminophen / administration & dosage
  • Acetaminophen / adverse effects*
  • Acetaminophen / therapeutic use
  • Adult
  • Analgesics / administration & dosage
  • Analgesics / adverse effects*
  • Analgesics / therapeutic use
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Barbiturates / administration & dosage
  • Barbiturates / therapeutic use
  • Caffeine / administration & dosage
  • Caffeine / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Foam Cells / ultrastructure*
  • Humans
  • Ibuprofen / administration & dosage
  • Ibuprofen / therapeutic use*
  • Kidney Glomerulus / pathology*
  • Nephrosis, Lipoid / chemically induced*
  • Nephrosis, Lipoid / pathology
  • Nephrotic Syndrome / chemically induced*
  • Nephrotic Syndrome / pathology
  • Pain / drug therapy
  • Pain / etiology
  • Tramadol / administration & dosage
  • Tramadol / therapeutic use

Substances

  • Analgesics
  • Anti-Inflammatory Agents, Non-Steroidal
  • Barbiturates
  • Acetaminophen
  • Tramadol
  • Caffeine
  • butalbital
  • Ibuprofen