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Bioorg Med Chem Lett. 2005 Dec 1;15(23):5307-10. Epub 2005 Sep 23.

Inhibitors of the serotonin transporter protein (SERT): the design and synthesis of biotinylated derivatives of 3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indoles. High-affinity serotonergic ligands for conjugation with quantum dots.

Author information

1
The Department of Chemistry, Vanderbilt University, Station B, 351822, Nashville, TN 37235-1822, USA.

Abstract

There is a growing demand for compounds with specificity for the serotonin transporter protein (SERT) that can be conjugated to cadmium selenide/zinc sulfide core shell nanocrystals. This letter describes the design and synthesis of two different biotinylated SERT antagonists that can be attached to streptavidin-coated cadmium selenide/zinc sulfide core shell nanocrystals.

PMID:
16183285
DOI:
10.1016/j.bmcl.2005.08.030
[Indexed for MEDLINE]

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