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Clin Lab Haematol. 2005 Oct;27(5):328-30.

A novel cytogenetic abnormality in Burkitt lymphoma associated with treatment resistant disease.

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1
Department of Haematology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, NSW, Australia.

Erratum in

  • Clin Lab Haematol. 2006 Feb;28(1):73. Durant, E [corrected to Durrant, E].

Abstract

We present a patient with deletion of IgH associated with the reciprocal translocation (8;14) in Burkitt lymphoma. The patient had treatment resistant disease and died 10 weeks after diagnosis. The deletion was detected by fluorescence in situ hybridization at diagnosis and again after failure of chemotherapy. To our knowledge this is the first report of such a deletion.

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