Do patients with frank haematuria referred under the two-week rule have a higher incidence of bladder cancer?

Ann R Coll Surg Engl. 2005 Sep;87(5):345-7. doi: 10.1308/003588405X60623.

Abstract

Introduction: The new NHS guaranteed that everyone with suspected cancer would be able to see a specialist within 2 weeks of their GP deciding that they need to be seen urgently. We investigated whether referrals under the two-week rule for frank haematuria results in a clinically significant advantage over normal referral pathways in patients with suspected bladder cancer.

Patients and methods: Patients referred for frank haematuria specifically under the two-week cancer rule were prospectively recorded over a 2-year period. Results of haematuria investigations were compared to a control group of routine frank haematuria referrals.

Results: Of the 32 patients in each group, four bladder cancers were found in the 2-week rule group and five bladder cancers were found in the control group (P > 0.05). The number of other demonstrable urological causes of frank haematuria was also the same in the two groups.

Conclusions: The incidence of bladder cancer and other urological pathologies is the same irrespective of referral pattern. It is not clear whether seeing such patients within 2 weeks confers any clinically significant advantage over conventional referral pathways. Not all patients with macroscopic haematuria are referred or seen under the two-week rule, this has considerable clinical governance implications for all departments of urology.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Cystoscopy / methods
  • Hematuria / etiology*
  • Humans
  • Incidence
  • Middle Aged
  • Prospective Studies
  • Referral and Consultation / standards*
  • Time Factors
  • Urinary Bladder Neoplasms / complications*
  • Urinary Bladder Neoplasms / diagnosis
  • Urinary Bladder Neoplasms / epidemiology